Ligand-targeted toxins (LTTs) are bioengineered molecules which are composed of a targeting component linked to a toxin that induces cell death once the LTT binds its target.Bispecific targeting allows for the simultaneous targeting Supplies of two receptors.In this review, we mostly focus on the epidermal growth factor receptor (EGFR) as a target.
Steel bracing may be used to enhance the seismic strength of RC frames.Concentric steel bracing generally reduces ductility, which is a key component of seismic design.To overcome the problem, ductile steel brace-RC frame systems are therefore usually Weight Management introduced in the form of eccentric braces.In the present study, the Off-Diagona
Abstract Although numerous observational studies associated underfeeding with poor outcome, recent randomized controlled trials (RCTs) have shown that early full nutritional support does not benefit critically ill patients and may induce dose-dependent harm.Some researchers have suggested that the absence of benefit in RCTs may be attributed to ove
ABSTRACT Historically, all efforts against tuberculosis were focused on rapid diagnosis and effective treatment to break the chain of transmission of Mycobacterium tuberculosis.However, in the last few years, more and more evidence has been found on the dramatic consequences of the condition defined as post-tuberculosis lung disease (PTLD).Approxim